The first-half goal from Guthrie was to be the only goal of the game when Northampton won 1-0 (1-0) away to Colchester in the England League Two.
The visiting team Northampton took an early lead when Jon Guthrie scored in the 22nd minute, making it 1-0.
In the next round, Colchester take on Mansfield at home at Colchester Community Stadium on Tuesday. Northampton play at home to Rochdale on Saturday.
